Ladies doing their first cycle of IUI or IVF.
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tinselcat
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Hi Dee, that may have been the trigger but you're not outside the window of positives yet - I have my fingers crossed for you.
I always used an OPK to test first as the line shows up quite nicely without the need for squinting, so it's a good marker for whether to test with the real thing (and cheaper too).
I always used an OPK to test first as the line shows up quite nicely without the need for squinting, so it's a good marker for whether to test with the real thing (and cheaper too).
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I'm so sorry dee, was so hoping for a positive result for you.
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I hope so too Dee. X
I wonder if anyone could help with a question I have. The doctors keep on about my eggs being a bit old, but would we have had 8 out of 17 fertilized if they weren't any good? Or was the quality of the eggs the reason the embryos didn't make it?
I wonder if anyone could help with a question I have. The doctors keep on about my eggs being a bit old, but would we have had 8 out of 17 fertilized if they weren't any good? Or was the quality of the eggs the reason the embryos didn't make it?
tinselcat
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Sorry to hear that Dee xx
Blueflower - old eggs sounds an odd thing to say, how old are you (if you don't mind me asking?) To get both 17 collected and 8 fertilised sounds like a great result to me xx i get the impression that this is a relatively new area of medical investigation and people just don't know why certain things do/don't happen, but there is lots of experimenting and researching to find out more. None of the embryologists (at a top NHS research hospital) could tell me why my embryos were so fragmented for example xx
Blueflower - old eggs sounds an odd thing to say, how old are you (if you don't mind me asking?) To get both 17 collected and 8 fertilised sounds like a great result to me xx i get the impression that this is a relatively new area of medical investigation and people just don't know why certain things do/don't happen, but there is lots of experimenting and researching to find out more. None of the embryologists (at a top NHS research hospital) could tell me why my embryos were so fragmented for example xx
tinselcat
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Sorry to hear that Dee xx
Blueflower - old eggs sounds an odd thing to say, how old are you (if you don't mind me asking?) To get both 17 collected and 8 fertilised sounds like a great result to me xx i get the impression that this is a relatively new area of medical investigation and people just don't know why certain things do/don't happen, but there is lots of experimenting and researching to find out more. None of the embryologists (at a top NHS research hospital) could tell me why my embryos were so fragmented for example xx
Blueflower - old eggs sounds an odd thing to say, how old are you (if you don't mind me asking?) To get both 17 collected and 8 fertilised sounds like a great result to me xx i get the impression that this is a relatively new area of medical investigation and people just don't know why certain things do/don't happen, but there is lots of experimenting and researching to find out more. None of the embryologists (at a top NHS research hospital) could tell me why my embryos were so fragmented for example xx
gemmainthesun
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Hi Blueflower
The fact you have 8 fertilised is a good sign.... but did they tell you the grades of them last time because the grades are a big indicator... so eg my friend got 3 or 4 fertilisede but they were all grade d low quality so she didn't have much chance.... my first ivf I had 1 A 1 B and lots of C's and im only 28 so initially they said they expected better but could have been a bad sperm sample that contributed too. 2nd cycle I took royal jelly and coq10 and even tho I had to freeze as produced 20, 15 were grade A and B so just goes to show cycles can be different, or maybe the supplements helped?
Anyway as for me, sorry not been o9n for a while. Due to start injections any day when AF arrives but still toying whether to or not, I ended up having another panic attack on holiday, cos I thought I felt a lump in my boob and then I started stressing over this weirdish mole that ive had for years but anyway it spiralled out of control and had another attack and was on valium for 3 or 4 days... went docs she said theres no lump in my boob so I guess it must be breat tissue that I just over exaggerated and the mole she said is fine but refered me in 6 months to dermatologist to make sure.... I was fine for few days but tonight ive started panicking over the bloody mole again! Shes also refered me to a psychologist or whatever as she thinks im developing or have an anxiety disorder!
Ive always been abit of a worrier but im sure this has all stemmed from the ivf/miscarriage and the 4 years TTC.... I think the stress has just got too much and is coming out in other ways.
BUT.... and only u lot will understand this, I really want to do my next round regardless lol I cant bear putting it off and admitting theres something the matter with me. I don't want them to put me on any anti depressants/anxiety meds cos I want to do the IVF... I just don't know what to do xxx
The fact you have 8 fertilised is a good sign.... but did they tell you the grades of them last time because the grades are a big indicator... so eg my friend got 3 or 4 fertilisede but they were all grade d low quality so she didn't have much chance.... my first ivf I had 1 A 1 B and lots of C's and im only 28 so initially they said they expected better but could have been a bad sperm sample that contributed too. 2nd cycle I took royal jelly and coq10 and even tho I had to freeze as produced 20, 15 were grade A and B so just goes to show cycles can be different, or maybe the supplements helped?
Anyway as for me, sorry not been o9n for a while. Due to start injections any day when AF arrives but still toying whether to or not, I ended up having another panic attack on holiday, cos I thought I felt a lump in my boob and then I started stressing over this weirdish mole that ive had for years but anyway it spiralled out of control and had another attack and was on valium for 3 or 4 days... went docs she said theres no lump in my boob so I guess it must be breat tissue that I just over exaggerated and the mole she said is fine but refered me in 6 months to dermatologist to make sure.... I was fine for few days but tonight ive started panicking over the bloody mole again! Shes also refered me to a psychologist or whatever as she thinks im developing or have an anxiety disorder!
Ive always been abit of a worrier but im sure this has all stemmed from the ivf/miscarriage and the 4 years TTC.... I think the stress has just got too much and is coming out in other ways.
BUT.... and only u lot will understand this, I really want to do my next round regardless lol I cant bear putting it off and admitting theres something the matter with me. I don't want them to put me on any anti depressants/anxiety meds cos I want to do the IVF... I just don't know what to do xxx
tinselcat
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Hi Gemma, do you have counselling option available? I always found that much better than medicine, and if problem is rooted in stress and worries then maybe talking about all the different things going on to someone dedicated to listening will be useful.
Have my fingers very much crossed for you xx
Have my fingers very much crossed for you xx
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Thanks ladies! How were they fragmented Tinselcat?
They didn't say what grade they were, just that they were good, so I guess B rather than A? The consultant said the quality could have been better so is putting me on different stimulation drugs this time.
I have been stressed too, don't think I was really over the IVF failure and events of the summer haven't helped. (See my journal!) I am going to try acupuncture again because it is supposed to boost results somehow. And thanks for reminding me to get some royal jelly! We can do this Gemma!
They didn't say what grade they were, just that they were good, so I guess B rather than A? The consultant said the quality could have been better so is putting me on different stimulation drugs this time.
I have been stressed too, don't think I was really over the IVF failure and events of the summer haven't helped. (See my journal!) I am going to try acupuncture again because it is supposed to boost results somehow. And thanks for reminding me to get some royal jelly! We can do this Gemma!
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tinselcat
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Hi Blueflower,
Ours were graded for 'quality' on a scale of 1-4, with 4 being the best (I think). We only ever had between 4-7 fertilise out of the 5-10 collected, and of them, 2-3 dividing at the appropriate rate, so it sounds like a much lower success rate than you managed.
Of the 2-3 that divided ok, the quality the first time round was one 3 and two 2s. Second time, a little better at two 3s (although the more celled-ones often were the worse quality ones) and one 2. Last time, we got one grade 3 with 10 cells (at day 3) and finally one they described as 'perfect' at grade 4 with 8 cells.
In all cases, despite a zillion notices about how they didn't want multiple pregnancies, they always transferred two embryos at day 3 (presumably as the odds of it working were pretty low and they didn't think anything would make it to blasto) and there was never anything worth freezing out of the rest by day 5.
First time round the eggs were collected some unknown 'cytoplasm' (a random blob) was noted in the cell - this may not have helped.
I think the fragmentation is part of the quality score, where they look for evenness/shape of the divided cells. The first two times round ours never looked anything like the pictures of 8-cell embryos you see on the internet, it was kind of more a mass of bubbles.
It sounds good that the consultant wants to try other options to give you a better result. Although I think you had a fantastic collection/fertilisation rate. If you see them again, may be worth asking how they scored on quality? xx
Ours were graded for 'quality' on a scale of 1-4, with 4 being the best (I think). We only ever had between 4-7 fertilise out of the 5-10 collected, and of them, 2-3 dividing at the appropriate rate, so it sounds like a much lower success rate than you managed.
Of the 2-3 that divided ok, the quality the first time round was one 3 and two 2s. Second time, a little better at two 3s (although the more celled-ones often were the worse quality ones) and one 2. Last time, we got one grade 3 with 10 cells (at day 3) and finally one they described as 'perfect' at grade 4 with 8 cells.
In all cases, despite a zillion notices about how they didn't want multiple pregnancies, they always transferred two embryos at day 3 (presumably as the odds of it working were pretty low and they didn't think anything would make it to blasto) and there was never anything worth freezing out of the rest by day 5.
First time round the eggs were collected some unknown 'cytoplasm' (a random blob) was noted in the cell - this may not have helped.
I think the fragmentation is part of the quality score, where they look for evenness/shape of the divided cells. The first two times round ours never looked anything like the pictures of 8-cell embryos you see on the internet, it was kind of more a mass of bubbles.
It sounds good that the consultant wants to try other options to give you a better result. Although I think you had a fantastic collection/fertilisation rate. If you see them again, may be worth asking how they scored on quality? xx
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You were up early Tinselcat! Thanks for the info.
I've just checked and on Day 3 we had 4 out of 5 IVF embryos at 8-9 cells in size, 2 out of 3 ICSI embryos were 7-8 cells, the target for day 3 was 8 cells. So 6 good ones. 2 were slower at only 5 cells but the embryologist said we should still have some good ones for transfer and maybe freezing as well on day 5.
I've just remembered that in our IVF failure consultation, we asked about the embryo quality and the consultant said he was surprised how quickly they deteriorated from day 3 to day 5. He said they made it to blastocyst stage but they were early blastocycts rather than mature ones. Apparently some clinics don't grade them any more. Or maybe they do but don't tell the patients! I might ask the nurse to look in the notes when I go for my scan next week!
I've just checked and on Day 3 we had 4 out of 5 IVF embryos at 8-9 cells in size, 2 out of 3 ICSI embryos were 7-8 cells, the target for day 3 was 8 cells. So 6 good ones. 2 were slower at only 5 cells but the embryologist said we should still have some good ones for transfer and maybe freezing as well on day 5.
I've just remembered that in our IVF failure consultation, we asked about the embryo quality and the consultant said he was surprised how quickly they deteriorated from day 3 to day 5. He said they made it to blastocyst stage but they were early blastocycts rather than mature ones. Apparently some clinics don't grade them any more. Or maybe they do but don't tell the patients! I might ask the nurse to look in the notes when I go for my scan next week!
gemmainthesun
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I personally wouldn't worry too much about grades cos u cant change then any more than your doing.... maybe best not to know xxx
gemmainthesun
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Just waiting for af so I can start treatment. Ive booked an urgent dermatology appointment about the mole for nxt fri just so hopefully its not on my mind during the cycle. I know there's deeper issues there but ive been refered for anxiety isdues so hopefully that will help
