Ladies doing IVF or IUI - 2015 (9 BFPs!)
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Got the results sheet, here goes:
Embryo 1 only had singles for chromosome 3, 9, 15, 16, 18, 20 & 22! It had an extra on 11 & 19! The other chromosomes were normal pairs.
Embryo 2 had an extra chromosome 4 & 16. Others were normal pairs.
Embryo 3 had an extra chromosome 8, all the rest normal pairs.
Embroyo 4 had an extra chromosome 1, 6, 10, 19 & XY/23. Only had a single for 2, 7, 16, 17 & 18. The rest were normal pairs.
Embryo 5 just had an extra chromosome 13, the rest normal pairs.
Embryo 6 only had a single for 10, 12, 15, 16, 21 & 22, the rest normal pairs.
Embryo 7 only had a single for chromosome 3 and had an extra for 9 and 22, the rest normal pairs.
Embryo 8 had an extra for chromosome 3 and only a single for 9 & 22, the rest normal pairs.
Ive been looking up what it all means. An extra chromosome for number 21 is Down Syndrome but a missing one causes birth defects or learning difficulties. One of them was for blood cancer and others have a huge list of diseases! It was really scary. Chromosome 8 duplication is associated with a lot of different syndromes. Chromosome 3 deletion is associated with autism. Im not sure what having 3 instead of a pair of sex chromosomes means either. I suppose it just means they cant join up properly and make a baby.
Very interesting but awful too.
Embryo 1 only had singles for chromosome 3, 9, 15, 16, 18, 20 & 22! It had an extra on 11 & 19! The other chromosomes were normal pairs.
Embryo 2 had an extra chromosome 4 & 16. Others were normal pairs.
Embryo 3 had an extra chromosome 8, all the rest normal pairs.
Embroyo 4 had an extra chromosome 1, 6, 10, 19 & XY/23. Only had a single for 2, 7, 16, 17 & 18. The rest were normal pairs.
Embryo 5 just had an extra chromosome 13, the rest normal pairs.
Embryo 6 only had a single for 10, 12, 15, 16, 21 & 22, the rest normal pairs.
Embryo 7 only had a single for chromosome 3 and had an extra for 9 and 22, the rest normal pairs.
Embryo 8 had an extra for chromosome 3 and only a single for 9 & 22, the rest normal pairs.
Ive been looking up what it all means. An extra chromosome for number 21 is Down Syndrome but a missing one causes birth defects or learning difficulties. One of them was for blood cancer and others have a huge list of diseases! It was really scary. Chromosome 8 duplication is associated with a lot of different syndromes. Chromosome 3 deletion is associated with autism. Im not sure what having 3 instead of a pair of sex chromosomes means either. I suppose it just means they cant join up properly and make a baby.
Very interesting but awful too.
phonixgirl
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Oh my goodness. Like you say, interesting but awful.
I still struggle to believe that every embryo you have produced for four years has been abnormal, and will continue to be so in the future. There's got to be a few that tick the right boxes.
I find the NK cells interesting too. Laura - it was definitely worth the money! I DO get ill so maybe that's not my issue (DH never does, but they're not in his body).
I rang the clinic earlier to check that a really heavy period after failed IVF is normal. She basically said to keep an eye on it. I was also chatting to a girl at work who is under the care of the fertility clinic too and she was asked if she had ever had an operation 'down there'. Well, I did have several hip operations as a baby and my mum noticed that they never put metal plates over my ovaries to protect them during X-rays as they were supposed to. I might bring this up at my next appointment - I hope it hasn't caused any long-term damage.
I still struggle to believe that every embryo you have produced for four years has been abnormal, and will continue to be so in the future. There's got to be a few that tick the right boxes.
I find the NK cells interesting too. Laura - it was definitely worth the money! I DO get ill so maybe that's not my issue (DH never does, but they're not in his body).
I rang the clinic earlier to check that a really heavy period after failed IVF is normal. She basically said to keep an eye on it. I was also chatting to a girl at work who is under the care of the fertility clinic too and she was asked if she had ever had an operation 'down there'. Well, I did have several hip operations as a baby and my mum noticed that they never put metal plates over my ovaries to protect them during X-rays as they were supposed to. I might bring this up at my next appointment - I hope it hasn't caused any long-term damage.
Hi blue flower, I'm so sorry to hear of your results. Like you say they are interesting but scary too. However, I can't believe that over these years every embryo you have made is abnormal. It just doesn't ring true. Have the clinic mentioned dhea? I know some ladies on other forms have taken it and it has improved egg quality. I have also read that BPA is not good for eggs and this can be found in all plastics. I read the book Rebecca Fet it's all about the egg it was very interesting. It was written by a scientist who struggled to conceive and was determined to improve egg quality.
Phoenixgirl I am sorry about your BFN. I feel your pain. I have never had a BFP either and after 2 transfers and 3 embryos I am now convinced I have an implantation issue or some form of killer cells. We had 10 eggs and only 4 fertilised but all 4 made it to day 5 and 3 were good enough to freeze and transfer. I have gone back to my doctor and asked them to refer me for a hysteroscopy. My follow up appointment from the clinic is not until the end of jan so hopefully this will speed it up. Can't believe it is a 2 month wait! I know it's hard but keep positive and focussed and your BFP will happen xx
Phoenixgirl I am sorry about your BFN. I feel your pain. I have never had a BFP either and after 2 transfers and 3 embryos I am now convinced I have an implantation issue or some form of killer cells. We had 10 eggs and only 4 fertilised but all 4 made it to day 5 and 3 were good enough to freeze and transfer. I have gone back to my doctor and asked them to refer me for a hysteroscopy. My follow up appointment from the clinic is not until the end of jan so hopefully this will speed it up. Can't believe it is a 2 month wait! I know it's hard but keep positive and focussed and your BFP will happen xx
phonixgirl
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Thanks hun xx
Blueflower, I just read about a lady whose eggs were all chromosomally abnormal one cycle, then she did tried IVF again and did CGH testing but this time some were normal and she got pregnant. So maybe it's not that stopping you from getting pregnant?
Tiptoes, I think I have implantation issues too. Have you had immune or NK cells testing? Most people with a high NK cell count don't really get ill, as Lauren said, so if you don't then it could ring alarm bells. I do though so maybe my issue is something else. X
Blueflower, I just read about a lady whose eggs were all chromosomally abnormal one cycle, then she did tried IVF again and did CGH testing but this time some were normal and she got pregnant. So maybe it's not that stopping you from getting pregnant?
Tiptoes, I think I have implantation issues too. Have you had immune or NK cells testing? Most people with a high NK cell count don't really get ill, as Lauren said, so if you don't then it could ring alarm bells. I do though so maybe my issue is something else. X
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What's dhea? I have stopped refilling plastic bottles and only use the safe washable ones now.
That's worrying about the x-rays Phoenixgirl.
AF lasted just a day and a half, its done that before after a stressful iui or ivf, must be due to the progesterone withdrawal and the rest should shed in a couple of weeks. Maybe that means I have plenty of natural progesterone and it wasn't ready to shed? Or maybe its just mucked up due to the horrible time I've had. I had at least a 10mm lining so there is more in there!
That's worrying about the x-rays Phoenixgirl.
AF lasted just a day and a half, its done that before after a stressful iui or ivf, must be due to the progesterone withdrawal and the rest should shed in a couple of weeks. Maybe that means I have plenty of natural progesterone and it wasn't ready to shed? Or maybe its just mucked up due to the horrible time I've had. I had at least a 10mm lining so there is more in there!
MariaIsabella
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Blueflower, in my previous post from the 3rd I write about my friend that got pregnant against all odds after taking dhea. Not sure if that was the reason but worth looking into.
Not sure what it is but its suppose to improve quality of eggs xx
Not sure what it is but its suppose to improve quality of eggs xx
phonixgirl
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Blueflower, you may find this useful: http://www.getpregnantover40.com/DHEA-and-fertility.htm Interesting that it says it reduces the number of chromosomally abnormal eggs!
I read earlier that PCOS means you have a higher ratio of chromosomally abnormal eggs for your age. I did not know this. I've not been on the metformin that long so I'm just hoping some of those frosties are ok!
I read earlier that PCOS means you have a higher ratio of chromosomally abnormal eggs for your age. I did not know this. I've not been on the metformin that long so I'm just hoping some of those frosties are ok!
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Thank you that looks good! I bet my consultant won't agree to it though!
I forgot to answer your comment Phoenixgirl about the lady whose embryos were much better the next cycle, I can hope!
I forgot to answer your comment Phoenixgirl about the lady whose embryos were much better the next cycle, I can hope!
phonixgirl
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I hope they are too! I hope mine are as well and we both get miracle BFPs! Think I'm living in a dream world...
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You have to hold onto hope! I only have a thin shred but its keeping me from despair!
Definitely look into that Blueflower, seems like a good route for you. What a horrible time you've had! Reading through your results, so detailed. It amazes me how much they can tell you. When's your next appointment? Xx
phonixgirl
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Good luck Laura, hope the steroids work xx
millielaura
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Oh that's so good Laura!
I just want my op done now to see if my hydro is affecting both tubes! Apparently sometimes the fluid can still affect the open one. In which case it'll be ivf. Same if my cycles stay short again like this one was. Which I don't mind the thought of, I'd rather do ivf with the immune protocol then stay on my steroids than start my steroids every tww. Hate those things
.
Is it unrealistic to want to stay working during it? Say if I worked morn and eve with appointments in afternoon?
Also because I want to freeze some eggs ranyway because of my low AFC, would doing ivf then freezing some embies be better? Doing both in one go? I know sometimes there is nothing to freeze though!
Would ivf help with the chemicals I have? Because they would make sure my lining is right for implantation? Although that could be the hydro and nk cells too?
I've seen a few threads of rm/c women getting their rainbow with ivf..I don't understand the diff though, is it because you are monitored constantly and taking the right medication to have the best chances of all going well? Xx
I just want my op done now to see if my hydro is affecting both tubes! Apparently sometimes the fluid can still affect the open one. In which case it'll be ivf. Same if my cycles stay short again like this one was. Which I don't mind the thought of, I'd rather do ivf with the immune protocol then stay on my steroids than start my steroids every tww. Hate those things
. Is it unrealistic to want to stay working during it? Say if I worked morn and eve with appointments in afternoon?
Also because I want to freeze some eggs ranyway because of my low AFC, would doing ivf then freezing some embies be better? Doing both in one go? I know sometimes there is nothing to freeze though!
Would ivf help with the chemicals I have? Because they would make sure my lining is right for implantation? Although that could be the hydro and nk cells too?
I've seen a few threads of rm/c women getting their rainbow with ivf..I don't understand the diff though, is it because you are monitored constantly and taking the right medication to have the best chances of all going well? Xx
millielaura
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A lot of the threads where from american sites though so not sure if its thr same here lol xxx
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I think its mostly because you produce more eggs so you have more chances in one. If you have 'freeze all' they freeze them straight after fertilization and you don't find out the quality until they thaw. They wouldn't transfer if you had a hydrosalpinx and would give you immune drugs if implantation was the issue.
If you stopped work for IVF you'd use up all your annual leave! Most scans are in the morning but consultations in the afternoon. How flexible is your job?
If you stopped work for IVF you'd use up all your annual leave! Most scans are in the morning but consultations in the afternoon. How flexible is your job?
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phonixgirl
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Take it as sick. Not the whole way through, but some. I thought I'd work all the way through then they told me I'd need EC off and the day after at least. I actually needed a week! I broke down at work though and told them all that was going on. They put it down as pregnancy related so it didn't affect any records xx
phonixgirl
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Also, in 'normal' situations they usually do a fresh cycle first then freeze any leftovers anyway for future use (you have to sign a consent form first, but that's it). Xxx
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Hi ladies!
Been away again for a while, DH and I haven't been doing any treatment cycles so we've had a long break (very long, think we stopped in April!) and I have my chat and plan next week for a FET cycle. We have one embryo on ice so taking a bit of a risk really but I wanted to do my frozen cycle first rather than add more embies to be frozen. My af seemed to be normal as my last 2 were both on the 9th bang on which, if you know me, you'll know is not normal at all as my af's are usually very far apart. But today is the 9th and of course, af is absent. ��
Anyways, how is everyone?
Hope everyone is well. X
Been away again for a while, DH and I haven't been doing any treatment cycles so we've had a long break (very long, think we stopped in April!) and I have my chat and plan next week for a FET cycle. We have one embryo on ice so taking a bit of a risk really but I wanted to do my frozen cycle first rather than add more embies to be frozen. My af seemed to be normal as my last 2 were both on the 9th bang on which, if you know me, you'll know is not normal at all as my af's are usually very far apart. But today is the 9th and of course, af is absent. ��
Anyways, how is everyone?
Hope everyone is well. X
