Hi lizzimay, I dont know what the signs of allergies are but would say eliminate the obvious things first - was the bottle too hot? In comparison to breastfeeding I guess its something they adapt to but perhaps thats the first thing to eliminate, I dont warm our formula to the accurate ozes it states as our lil miss likes room temp or a little bit warmer so if heating 7oz bottle will set to 3oz from fridge...otherwise not sure what to suggest, does it appear to be causing her discomfort? I would see if another brand of formula helps or even another bottle type as she may have allergies to the type of plastic but I wouldnt get too worried, just try doing exactly the same again and see if goes red/remains red from before/gets worse then perhaps seek advice...if you have any other formula brands/bottle brands in the house then perhaps try those....hope this helps...