Nearly all my stuff will be second hand, and def the big stuff, but will only be used for this - my last baby, and not for all my kids if your a first timer. I would never buy a second hand matress, or carseats like others have said, my car seat is coing from my sister and she brought it new 2 years ago and I know it has not been in any accidents as it's her, so only this reason I will be using it. The cot is coming from friends , good quality, but well used for 4 kids! so new matress all the way for my little baby.
Clothes and baby plastic toys can be washed and I only buy very good quality ones, you have to check them thoroughly and be really fussy,
I am on the hunt for a baby bath from the last car boots of the summer, so fingers crossed the rain holds off.