Both my girls are prone to car sickness. Ive found it happens soon after they've had anything too liquidy like porridge. Its gross as it gets into all the crevices of the car seat and the car stinks for days. Theres not much you can take in terms of medication at that age to help. Ive developed a 'sick kit' which contains disposable gloves, hand gel, dettol spray, a sick bowl and nappy bags to collect the sick. Now that is only useful if there is more than one adult in the car. I also made them both sick bibs which have a big pocket so if they're sick, the bib and pocket catch it. This makes the cleaning up aftermath so much easier.
Also if I know there is a longish journey involved where possible the meal before hand will be very dry e.g. toast. Also if i can time the journey when i know they'll be tired enough to sleep that also helps.
However I don't drive much so I imagine for me it's a bit easier than for someone who uses the car much more frequently.