PGS on already frozen embryos

[hopefulmum2014]

I was hoping for some advice or thoughts on Pre Implantation Genetic Screening.
I had my first round of ivf this which worked but sadly miscarried at 9 weeks.
The test showed the baby had chromosome abnormality of monosomy X which my consultant said is common in early miscariage.
I am 34 & I have four top grade 5 day blastocyst frozen, we are hopefully having a December transfer. My clinic have wrote to me to say they do offer PGS.

Does anyone have any experience or thoughts on PGS? My understanding is that it is usually done with a fresh IVF cycle, if it is possible to do on already frozen embryos would that not put them through too much trauma?

I do have an appointment next week with the clinic but would appreciate anyones thoughts.

xxx

 

[phonixgirl]

Hi hun

Blueflower had PGS and found all of her eggs were chromosomally abnormally even though they looked great from the outside. She had had multiple IVF failures though. She used a donor and now has her twin boys.

It's something I've thought about but the clinic has never mentioned it to me - they just keep saying it's bad luck. I guess if I was in your situation I would need to know if the chances of there being the same or any other chromosomal abnormality is higher than normal (high in general?).

You're not old biologically so that's not an issue for now but that's not to say your eggs' chromosomes match.

As for the frozen thing... I'm not sure if they can do it on frozen eggs and I don't think I'd want it done on them (as you say, more stress, but also they wouldn't be looking at ALL the eggs straight as they come out). My understanding of it is you have a fresh cycle, all retrieved eggs are screened and that will give you an idea of if you need to use a donor/they can select the chromosomally normal eggs.