the big asprin debate

Discussion in 'Trying to Conceive' started by Tina18, Mar 5, 2016.

  1. Tina18

    Tina18 Well-Known Member

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    Hello everyone

    I hope your all having a fab weekend.

    So I have done tonnes of research on recurrent miacarriages (my oh says I'm going to be an expert soon!!)

    Anyway I have read so many positive outcomes of taking asprin when you get your BFP and to take throughout your pregnancy, here are some articles that a friend shared with me if your interested, she also shared below a link on a documentary called waiting for a heartbeat which I watched this morning. I wish I spoke to the lady in work after my first miscarriage, she ended up seeing a top fertity specialist in London who she finally had twins through and he recommended Asprin to her and she took it throughout pregnancy.

    Lucky for me I spoke to my doctor and begged her to to a blood test (she won't do it until 2 -3 months after my miscarriage though but my oh doesn't want to wait) to check if ive got antiphospholipid syndrome which means you have sticky blood and its more likely to clot. Interestingly in the documentary they touch on the fact that around 10 weeks, the function of the placenta is key and this is where the blood clotting can cause issue - both of my pregnancies have ended around 10 weeks.

    What are your thoughts on asprin? When I mentioned it to the Doctor she said she wouldn't recommend it as it could cause bleeding, for me if I get pregnant again not doing anything is a massive risk. Also in the documentary they said thay you should only take asprin when you get your BFP.

    I hope you find the links below useful:


    http://www.mirror.co.uk/lifestyle/health/daily-aspirin-can-help-women-6672104

    http://www.mirror.co.uk/lifestyle/health/tv-star-claire-sweeney-saved-5187597

    http://youtu.be/dPaQziLalnc This is a documentary about St Mary's and Lesley Regan, renowned for her investigations into recurrent miscarriage. She's another advocate of aspirin - see piece on Claire Sweeney above, she consulted with her after 2 miscarriages and she prescribed only aspirin.

    http://www.nytimes.com/2008/03/25/health/25brod.html?_r=0

    http://www.dailymail.co.uk/health/a...painkiller-reduce-risk-women-miscarrying.html

    http://www.nhs.uk/Conditions/Hughes-syndrome/Pages/Introduction.aspx

    http://www.independent.co.uk/life-s...ashioned-witchcraft-but-it-works-1234794.html
     
  2. snowbee

    snowbee Well-Known Member

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    Here are a couple more for you that I've read. My personal view is I wouldn't take it unless I had a problem that asprin would help with, so I wouldn't just take a random punt. I've had two mcs too. Obviously I'm desperate for a sticky bfp and I'm willing to do anything that will increase that chance but I won't take something that could make things worse for me. I'm also waiting on blood test results to see if asprin would be beneficial for me, I won't be taking it if it turns out I don't have an issue.

    "Aspirin does not improve implantation rate and reduces follicle growth

    We performed a randomized analysis of 145 infertile women with a mean age of 29.6 years who underwent cycles of IVF. Patients received 100 mg of aspirin or placebo daily. Aspirin was started on the 21st of their preceding menstrual cycle and it was continued until menstruation or a negative pregnancy test. Pregnant women received the medication until 12 weeks of pregnancy. The main outcome measures were number of follicles >or=15 mm, number of oocytes retrieved, serum estrogen levels, cancellation rate, Ovarian Hyperstimulation Syndrome (OHSS) occurrence, number of embryos transferred, and implantation and pregnancy rates. RESULTS: There were statistically significant differences between the treatment group and the control group in the number of follicles (7.4 versus 9.0) and OHSS occurrence (5.6% versus 23.3%) but not in the other measures. CONCLUSION: The addition of aspirin low dose (100 mg/daily) to the standard long protocol for oocyte retrieval did not improve implantation and pregnancy rates in unselected patients undergoing IVF cycles.

    http://www.ncbi.nlm.nih.gov/pubmed/17457441


    Aspirin may interfere with implantation and cause certain birth defects
    In theory, aspirin has both positive and negative effects on reproduction. Aspirin, which suppresses cyclooxygenase, has the potential to interfere with implantation, but also has the potential to support the maintenance of pregnancy. Aspirin is prescribed with increasing frequency to reduce the risk of maternal thrombosis and reduce the risk of miscarriage and poor pregnancy outcome. Aspirin alone, however, is not considered sufficient to prevent thrombosis and even in women with the antiphospholipid syndrome, the question as to whether low-dose aspirin improves pregnancy outcomes has not been answered affirmatively. Aspirin has potential risks. Aspirin inhibits platelet function and can contribute to maternal and fetal bleeding. Aspirin crosses the placenta. Although aspirin has not been associated with other congenital anomalies, it has been associated with an increased risk of vascular disruptions, particularly gastroschisis and possibly premature closure of the ductus arteriosus. Nonetheless, large trials demonstrate low-dose aspirin's relative safety and generally positive effects on reproductive outcomes.
    http://www.ncbi.nlm.nih.gov/pubmed/18081940"
     
  3. Tina18

    Tina18 Well-Known Member

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    Thanks snowbee that's intersting, I know it sounds silly but I was kinda sad reading that as I felt like I had a cure or a way to prevent it happening again... I guess im just clutching at straws.

    I hope you don't mind me asking but how soon after your last MC did they do the blood tests on you? Xxxx
     
  4. snowbee

    snowbee Well-Known Member

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    I'm still waiting for the appointment, I must chase it up. I've let it slide a little as I'm also on a recurrent mc trial, they have taken heaps of my blood so far and not mentioned anything relating to this.

    I don't think there is a miracle cure or a perfect answer I'm afraid. The human body is so complex it is amazing any of us are alive at all.
     

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