We used both infacol and Gripe Water together, I found that the Infacol was better at making Theo give a good burp at the end of his bottle, but i found the gripe water worked in settling his tummy (as you could hear the wind wirling around). but in all honesty i thought they worked for the first few weeks but we didnt get on Very well with them and Theo used to be sick with the gripe water more often then not. but in answer to your question . yup we used them together!